Born in Japan, she started taking piano lessons when she was five years old. While a student in primary school, she won the music competition for Pan-Japanese students. Hisako continued studying under the supervision of Professor Takahiro Sonoda, and graduated with honors from the Kyoto University of Arts. She went on to develop a steady and intense music career and she eventually became a professor at her Alma Mater. Hisako entered the European music scene by winning the Honorary Diploma at the Maria Canals International music competition and the Gold Award at the Piano 80 competition in Switzerland. She has taken various Masters including the Mozarteum in Salzburg (Internationale Sommerakademiekurs), Solistenklasse with Hans Leygraf at the Hochschule für Musik und Theater Hannover, a course with Christoph Lieske in Konservatorium Winthertur that earned her the Solistendiplom degree, and more recently a Master Course of Spanish Music with Alicia de Larrocha.
Hisako Hiseki has offered various performances in Spain (Palau de la Musica Catalana, Festival del Castell de Peralada, Templo de la Sagrada Familia, Auditorio Pau Casals, Festival Grec de Barcelona, Auditorio Enrique Granados, Teatro Fortuny, Teatro Faràndula…), Japan (Tokyo Bunka Kaikan, Symphony Hall en Osaka, Ai-Hall, Aiphonic-Hall, Acros in Fukuoka…), Switzerland, Germany and France. She has also played as a soloist with well-known orchestras in performances that have aired on the Spanish, Japanese and Swiss radio and television. Hisako has taught master classes on Spanish music in Japan. In 1986 she started a series of annual charity concerts aimed at raising money for the construction of the Sagrada Familia. She has been a member of the jury at the Xavier Montsalvatge XXth Century Piano Music Award and nowadays she is a member of the jury at the Barcelona Young Musicians Festival.